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Stem cell-derived cardiomyocytes expressing a dominant negative pacemaker HCN4 channel do not reduce the risk of graft-related arrhythmias

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BackgroundHuman pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI). but their transplantation gives rise to transient ventricular tachycardia (VT) in large-animal MI models. representing a major hurdle to translation. Our group previously reported that these arrhythmias arise from a focal mechan... https://www.poolsproductscanadas.shop/product-category/jandy-aqualink-tcx-parts/
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