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Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia

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Background The EVI1 gene (3q26) codes for a zinc finger transcription factor with important roles in both mammalian development and leukemogenesis. Over-expression of EVI1 through either 3q26 rearrangements. MLL fusions. or other unknown mechanisms confers a poor prognosis in acute myeloid leukemia. https://unitedssports.shop/product-category/inline-skates-senior/
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