Abstract Background It has been reported that the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway regulates erythropoietin (EPO)-induced survival. proliferation. and maturation of early erythroid progenitors. Erythroid cell proliferation and survival have also been related to activation of the JAK-STAT pathway. https://www.chiggate.com/lumishine-lumi-10-permanent-creme-color-8n-cheap/