Abstract Background Imbalance between protein synthesis and endoplasmic reticulum (ER) capacity to modify and fold proteins lead to the accumulation of unfolded proteins resulting in ER stress and apoptosis. Chaperones are major defense molecules assisting in protein folding. transport. and cellular signaling. https://www.roneverhart.com/Pica-Limon-Salt-Lemon-Spicy-Powder-Packs-100-Piece-Bag/